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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
22.42
Human Site:
S427
Identified Species:
37.95
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
S427
N
G
C
L
G
H
G
S
L
T
D
I
S
Q
P
Chimpanzee
Pan troglodytes
XP_511801
843
90571
S578
N
G
C
L
G
H
G
S
L
T
D
I
S
Q
P
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
S516
N
G
C
L
G
H
G
S
L
T
D
I
S
Q
P
Dog
Lupus familis
XP_548291
727
78319
S462
N
G
C
L
G
H
G
S
L
N
D
I
S
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
N433
N
G
C
L
G
H
G
N
L
T
D
I
S
Q
P
Rat
Rattus norvegicus
NP_001099274
698
75236
S433
N
G
C
L
G
H
G
S
L
T
D
I
S
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
S411
S
G
S
L
G
H
G
S
F
T
D
V
G
Q
P
Chicken
Gallus gallus
XP_415822
728
79098
N433
N
G
C
L
G
H
G
N
F
T
D
V
S
Q
P
Frog
Xenopus laevis
Q7ZZC8
944
104521
A446
C
L
G
V
N
Q
S
A
G
S
E
V
L
E
P
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
N434
N
G
C
L
G
H
G
N
F
N
D
V
T
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
Q673
H
N
K
L
N
L
T
Q
R
V
G
F
F
T
K
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
S211
G
N
Q
R
R
S
A
S
R
V
S
S
A
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
V371
V
R
A
S
A
S
P
V
R
P
R
Q
P
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
E508
N
P
R
M
I
F
G
E
E
P
T
S
T
D
K
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
66.6
80
6.6
66.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
80
93.3
46.6
86.6
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
8
0
0
0
0
8
0
0
% A
% Cys:
8
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
65
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
22
0
0
8
8
0
0
% F
% Gly:
8
65
8
0
65
0
72
0
8
0
8
0
8
0
0
% G
% His:
8
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
43
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
15
% K
% Leu:
0
8
0
72
0
8
0
0
43
0
0
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
65
15
0
0
15
0
0
22
0
15
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
0
15
0
0
8
0
72
% P
% Gln:
0
0
8
0
0
8
0
8
0
0
0
8
0
65
0
% Q
% Arg:
0
8
8
8
8
0
0
0
22
0
8
0
0
15
0
% R
% Ser:
8
0
8
8
0
15
8
50
0
8
8
15
50
0
15
% S
% Thr:
0
0
0
0
0
0
8
0
0
50
8
0
15
8
0
% T
% Val:
8
0
0
8
0
0
0
8
0
15
0
29
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _